chemical synthesis & scale-up

SYNTHIA™ Retrosynthesis Software

Streamline synthesis, increase yields, and accelerate novel pathway discovery from weeks to minutes—with unbiased, bench-validated insights.

Discovery at Your Fingertips

Expert-coded by chemists, SYNTHIA™ lets you customize synthetic routes, optimize reactions, and access millions of starting materials for faster, efficient molecule discovery.

21+

Years of development and validation

120k

hand-coded reaction rules

12M+

available starting materials

Quickly Go from Imagining What’s Possible to 
Testing What’s Probable

See how our industry-leading retrosynthesis platform successfully designs and plans routes for target molecules based on your requirements.

Choose Your Search Mode Leverage Your Inventory Customize Your Parameters Visualize Your Pathway

Explore and Compare Unique Pathways

Select the type of retrosynthesis analysis to be performed—manual, automatic, or batch—and the target molecule from known and unknown compounds. ​

Optimize Your Time
in the Lab

Find pathways that start with commercially available or known building blocks—or incorporate your custom inventory—to clear logistical hurdles.

Maximize Lab Productivity

Increase efficiency and reduce costs by defining preferred reactions, starting materials, stop conditions, scoring functions, price thresholds, and more.

Visualize Your Pathway

Explore detailed retrosynthesis pathways with interactive visuals, graphs, filtering options, and step-by-step analysis for lab-ready results.

Benefits of SYNTHIA™ in Chemical Synthesis

Simplify Route Design

Quickly scan hundreds of synthesis pathways to find the best route for your project needs.

Save Time and Reduce Costs

Identify the most cost-effective routes to your target molecule with advanced filtering tools.

Support Greener Chemistry

Customize your search to avoid hazardous reagents and discover sustainable alternatives.

Generate New Ideas and IP

Unlock unique syntheses for patentable discoveries and build novel molecules efficiently.

Licensing

Licensing packages that suit your needs

SYNTHIA™ is highly customizable to meet the everyday demands of synthetic organic chemists, enabling greater efficiency and productivity.  Contact us today for a licensing package that fits your needs.

ENTERPRISE LICENSES

Flexible License Terms

  • Individual & Enterprise Licenses
  • 6-36 Month Term Lengths
  • SYNTHIA™ Lite for Individual or Short-Term

Projects Service

  • Training & Video Tutorials
  • Technical support
  • On-Site Workshops Available

Optional Add-Ons

  • Custom inventory integration
  • Single sign-on (SSO)
  • API access

SYNTHIA™ API

Connect SYNTHIA™ with your preferred cheminformatics software for high-throughput pathway design and molecular synthesis feasibility.

SYNTHIA™ Lite

Interested in first trying a limited version of SYNTHIA™ retrosynthesis software? Click the link below to create a free SYNTHIA™ Lite account.

GET STARTED

Ready to Revolutionize Your Retrosynthesis?

Connect with our team to see how SYNTHIA™ can streamline your synthesis planning and accelerate your research. Request a demo today!






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“SYNTHIA™ is useful to use as early as you can in the route selection process. Far and away better than some of the other retrosynthesis software in terms of stereochemistry and predicting bond disconnections.”

“From a chemistry perspective there’s a lot of excitement that SYNTHIA™ represents everything we are looking for. It’s a disruptive technology, and it’s really disruptive if you don’t have it.”

“Unlike other tools, SYNTHIA™ doesn’t show anything illogical. Intuitive, easy to use and navigate. I like the user interface.”

“SYNTHIA™ came up with suggestions I wouldn’t have considered otherwise, which is really what we’re looking for in a tool like this.”

Resources

Explore our latest white papers, webinars, and more to stay informed about cutting-edge advancements in AI-powered drug discovery and retrosynthesis.

White Papers

Chemistry World: SYNTHIA™ & Green Chemistry

Reduce step counts, improve yields and atom economy while reducing environmental impact, all with a little computational help.

White Papers Chemical Synthesis

Webinars

Greener Chemical Synthesis Design

Webinars Chemical Synthesis

News & Events

Stay up to date with recent news articles and upcoming conferences where you can connect with our experts.